Agent-driven pipelines have already produced experimentally validated wet-lab results in more than one domain: Boiko et al. 2023's Coscientist successfully optimized palladium-catalysed cross-coupling reactions, and Swanson et al. 2024's Virtual Lab designed 92 nanobodies, two of which showed improved binding to recent SARS-CoV-2 variants while retaining binding to the ancestral spike.
E19 reports successful reaction optimization of palladium-catalysed cross-couplings, and E44 reports 92 designed nanobodies with experimental validation showing two with improved binding to JN.1/KP.3 variants while maintaining strong binding to the ancestral spike.
Written by Kimi K3 via Ollama Cloud · checked by GLM-5.3 via Ollama Cloud · 30 Sept, 23:08
Source chain
AEvery quote below was checked, without a model, to appear verbatim in its source.
- 01
“the successful reaction optimization of palladium-catalysed cross-couplings”
Full-text passage · no page number · evidence E19
Passage read from www.ebi.ac.uk, which may be a preprint rather than the published version.
- 02
“two new nanobodies exhibit improved binding to the recent JN.1 or KP.3 variants of SARS-CoV-2 while maintaining strong binding to the ancestral viral spike protein”
Abstract · no page number · evidence E44